Tay Lab

2019

17.

Tay TL*, Carrier M, Tremblay MÈ* (2019) Physiology of Microglia. In: Verkhratsky A., Ho M., Zorec R., Parpura V. (eds) Neuroglia in Neurodegenerative Diseases. Advances in Experimental Medicine and Biology, vol 1175. Springer, Singapore *corresponding author

16.

Costa Jordão MJ, Brendecke SM, Sankowski R, Sagar, Locatelli G, Tai Y-H, Tay TL, Schramm E, Armbruster S, Hagemeyer N, Mai D, Çiçek Ö, Falk T, Kerschensteiner M, Grün D, Prinz M (2019). Single-cell profiling of the myeloid compartment identifies new cell populations with distinct fates during neuroinflammation. Science, 363: eaat7554.

15.

Falk T, Mai D, Bensch R, Çiçek Ö, Abdulkadir A, Marrakchi Y, Böhm A, Deubner J, Jäckel Z, Seiwald K, Dovzhenko A, Tietz O, Dal Bosco C, Walsh S, Saltukoglu D, Tay TL, Prinz M, Palme K, Simons M, Diester I, Brox T, Ronneberger O (2019). U-Net: deep learning for cell counting, detection, and morphometry. Nat Methods, 16: 67-70.

2018

14.

Shemer A#, Grozovski J#, Tay TL#, Tao J, Süß P, Volaski A, Gross M, Kim J-S, David E, Chappell-Maor L, Thielecke L, Glass CK, Cornils K, Prinz M, Jung S (2018). Engrafted parenchymal brain macrophages differ from host microglia in transcriptome, epigenome and responsiveness to challenge. Nat Commun, 9: 5206. #co-first author

13.

Tay TL*#, Sagar#, Dautzenberg J, Grün D*, Prinz M* (2018). Unique microglia recovery population revealed by single-cell RNAseq following neurodegeneration. Acta Neuropathol Commun, 6: 87. *corresponding author, #co-first author

12.

Datta M, Staszewski O, Raschi E, Frosch M, Hagemeyer N, Tay TL, Blank T, Kreutzfeldt M, Merkler D, Ziegler-Waldkirch S, Matthias P, Meyer-Luehmann M, Prinz M (2018). Histone deacetylases 1 and 2 regulate microglia function during development, homeostasis and neurodegeneration in a context-dependent manner. Immunity, 48(3): 514-529.

11.

Weinhard L, d’Errico P, Tay TL* (2018). Headmasters: microglial regulation of learning and memory in health and disease. AIMS Mol Sci, 5: 63-89. *corresponding author

10.

Tay TL*, Béchade C, d’Andrea I, St-Pierre M-K, Henry MS, Roumier A*, Tremblay M-È* (2018). Microglia gone rouge: impacts on psychiatric disorders across the lifespan. Front Mol Neurosci, 10: 421. *corresponding author

2017

9.

Tay TL*, Mai D, Dautzenberg J, Fernandez-Klett F, Lin G, Sagar, Datta M, Drougard A, Stempfl T, Ardura-Fabregat A, Staszewski O, Margineanu A, Sporbert A, Steinmetz L, Pospisilik JA, Jung S, Priller J, Grün D,Ronneberger O, Prinz M* (2017). A new fate mapping system reveals context-dependent random or clonal expansion of microglia. Nat Neurosci, 20(6): 793-803. *corresponding author

8.

Tay TL*, Savage JC, Hui CW, Bisht K, Tremblay M-È* (2017). Microglia across the lifespan: from origin to function in brain development, plasticity and cognition. J Physiol, 595(6): 1929-1945. *corresponding author

2016

7.

Tay TL, Hagemeyer N, Prinz M (2016). The force awakens: insights into the origin and formation of microglia. Curr Opin Neurobiol, 39: 30-37.

2015

6.

Goldmann T, Zeller N, Raasch J, Kierdorf K, Frenzel K, Ketscher L, Basters A, Staszewski O, Brendecke SM, Spieß A, Tay TL, Kreutz C, Timmer J, Mancini GMS, Blank T, Fritz G, Biber K, Lang R, Malo D, Merkler D, Heikenwalder M, Knobeloch K-P, Prinz M (2015). USP18 lack in microglia causes destructive interferonopathy of the mouse brain. EMBO J, 34(12): 1612-1629.

2014

5.

Prinz M, Tay TL, Wolf Y, Jung S (2014). Microglia: unique and common features with other tissue macrophages. Acta Neuropathol, 128(3): 319-331.

2013

4.

Goldmann T, Tay TL, Prinz M (2013). Love and death: microglia, NLRP3 and the Alzheimer’s brain. Cell Res, 23(5): 595-596.

2011

3.

Tay TL, Ronneberger O, Ryu S, Nitschke R, Driever W (2011). Comprehensive catecholaminergic projectome analysis reveals single-neuron integration of zebrafish ascending and descending dopaminergic systems. Nat Commun, 2: 171

2006

2.

Tay TL, Lin Q, Seow TK, Tan KH, Hew CL, Gong Z (2006). Proteomic analysis of protein profiles during early development of the zebrafish, Danio rerio. Proteomics, 6(10): 3176-3188.

2003

1.

Gong Z, Wan H, Tay TL, Wang H, Chen M, Yan T (2003). Development of transgenic fish for ornamental and bioreactor by strong expression of fluorescent proteins in the skeletal muscle. Biochem Biophys Res Comm, 308(1): 58-63.